Purpose

The ISS was originally intended to be a laboratory, observatory, and factory while providing transportation, maintenance, and a low Earth orbit staging base for possible future missions to the Moon, Mars, and asteroids. However, not all of the uses envisioned in the initial memorandum of understanding between NASA and Roscosmos have come to fruition. In the 2010 United States National Space Policy, the ISS was given additional roles of serving commercial, diplomatic, and educational purposes.

Scientific researchedit

The ISS provides a platform to conduct scientific research, with power, data, cooling, and crew available to support experiments. Small uncrewed spacecraft can also provide platforms for experiments, especially those involving zero gravity and exposure to space, but space stations offer a long-term environment where studies can be performed potentially for decades, combined with ready access by human researchers.

The ISS simplifies individual experiments by allowing groups of experiments to share the same launches and crew time. Research is conducted in a wide variety of fields, including astrobiology, astronomy, physical sciences, materials science, space weather, meteorology, and human research including space medicine and the life sciences. Scientists on Earth have timely access to the data and can suggest experimental modifications to the crew. If follow-on experiments are necessary, the routinely scheduled launches of resupply craft allows new hardware to be launched with relative ease. Crews fly expeditions of several months' duration, providing approximately 160 person-hours per week of labour with a crew of six. However, a considerable amount of crew time is taken up by station maintenance.

Perhaps the most notable ISS experiment is the Alpha Magnetic Spectrometer (AMS), which is intended to detect dark matter and answer other fundamental questions about our universe and is as important as the Hubble Space Telescope according to NASA. Currently docked on station, it could not have been easily accommodated on a free flying satellite platform because of its power and bandwidth needs. On 3 April 2013, scientists reported that hints of dark matter may have been detected by the AMS. According to the scientists, "The first results from the space-borne Alpha Magnetic Spectrometer confirm an unexplained excess of high-energy positrons in Earth-bound cosmic rays".

The space environment is hostile to life. Unprotected presence in space is characterised by an intense radiation field (consisting primarily of protons and other subatomic charged particles from the solar wind, in addition to cosmic rays), high vacuum, extreme temperatures, and microgravity. Some simple forms of life called extremophiles, as well as small invertebrates called tardigrades can survive in this environment in an extremely dry state through desiccation.

Medical research improves knowledge about the effects of long-term space exposure on the human body, including muscle atrophy, bone loss, and fluid shift. This data will be used to determine whether high duration human spaceflight and space colonisation are feasible. As of 2006update, data on bone loss and muscular atrophy suggest that there would be a significant risk of fractures and movement problems if astronauts landed on a planet after a lengthy interplanetary cruise, such as the six-month interval required to travel to Mars.

Medical studies are conducted aboard the ISS on behalf of the National Space Biomedical Research Institute (NSBRI). Prominent among these is the Advanced Diagnostic Ultrasound in Microgravity study in which astronauts perform ultrasound scans under the guidance of remote experts. The study considers the diagnosis and treatment of medical conditions in space. Usually, there is no physician on board the ISS and diagnosis of medical conditions is a challenge. It is anticipated that remotely guided ultrasound scans will have application on Earth in emergency and rural care situations where access to a trained physician is difficult.

In August 2020, scientists reported that bacteria from Earth, particularly Deinococcus radiodurans bacteria, which is highly resistant to environmental hazards, were found to survive for three years in outer space, based on studies conducted on the International Space Station. These findings support the notion of panspermia, the hypothesis that life exists throughout the Universe, distributed in various ways, including space dust, meteoroids, asteroids, comets, planetoids or contaminated spacecraft.

Freefalledit

Gravity at the altitude of the ISS is approximately 90% as strong as at Earth's surface, but objects in orbit are in a continuous state of freefall, resulting in an apparent state of weightlessness. This perceived weightlessness is disturbed by five separate effects:

• Drag from the residual atmosphere.
• Vibration from the movements of mechanical systems and the crew.
• Actuation of the on-board attitude control moment gyroscopes.
• Thruster firings for attitude or orbital changes.
• Gravity-gradient effects, also known as tidal effects. Items at different locations within the ISS would, if not attached to the station, follow slightly different orbits. Being mechanically interconnected these items experience small forces that keep the station moving as a rigid body.

Researchers are investigating the effect of the station's near-weightless environment on the evolution, development, growth and internal processes of plants and animals. In response to some of this data, NASA wants to investigate microgravity's effects on the growth of three-dimensional, human-like tissues, and the unusual protein crystals that can be formed in space.

Investigating the physics of fluids in microgravity will provide better models of the behaviour of fluids. Because fluids can be almost completely combined in microgravity, physicists investigate fluids that do not mix well on Earth. In addition, examining reactions that are slowed by low gravity and low temperatures will improve our understanding of superconductivity.

The study of materials science is an important ISS research activity, with the objective of reaping economic benefits through the improvement of techniques used on the ground. Other areas of interest include the effect of the low gravity environment on combustion, through the study of the efficiency of burning and control of emissions and pollutants. These findings may improve current knowledge about energy production, and lead to economic and environmental benefits. Future plans are for the researchers aboard the ISS to examine aerosols, ozone, water vapour, and oxides in Earth's atmosphere, as well as cosmic rays, cosmic dust, antimatter, and dark matter in the Universe.

Explorationedit

The ISS provides a location in the relative safety of low Earth orbit to test spacecraft systems that will be required for long-duration missions to the Moon and Mars. This provides experience in operations, maintenance as well as repair and replacement activities on-orbit, which will be essential skills in operating spacecraft farther from Earth, mission risks can be reduced and the capabilities of interplanetary spacecraft advanced. Referring to the MARS-500 experiment, ESA states that "Whereas the ISS is essential for answering questions concerning the possible impact of weightlessness, radiation and other space-specific factors, aspects such as the effect of long-term isolation and confinement can be more appropriately addressed via ground-based simulations". Sergey Krasnov, the head of human space flight programmes for Russia's space agency, Roscosmos, in 2011 suggested a "shorter version" of MARS-500 may be carried out on the ISS.

In 2009, noting the value of the partnership framework itself, Sergey Krasnov wrote, "When compared with partners acting separately, partners developing complementary abilities and resources could give us much more assurance of the success and safety of space exploration. The ISS is helping further advance near-Earth space exploration and realisation of prospective programmes of research and exploration of the Solar system, including the Moon and Mars." A crewed mission to Mars may be a multinational effort involving space agencies and countries outside the current ISS partnership. In 2010, ESA Director-General Jean-Jacques Dordain stated his agency was ready to propose to the other four partners that China, India and South Korea be invited to join the ISS partnership. NASA chief Charles Bolden stated in February 2011, "Any mission to Mars is likely to be a global effort". Currently, US federal legislation prevents NASA co-operation with China on space projects.

Education and cultural outreachedit

The ISS crew provides opportunities for students on Earth by running student-developed experiments, making educational demonstrations, allowing for student participation in classroom versions of ISS experiments, and directly engaging students using radio, videolink, and email. ESA offers a wide range of free teaching materials that can be downloaded for use in classrooms. In one lesson, students can navigate a 3D model of the interior and exterior of the ISS, and face spontaneous challenges to solve in real time.

JAXA aims to inspire children to "pursue craftsmanship" and to heighten their "awareness of the importance of life and their responsibilities in society". Through a series of education guides, students develop a deeper understanding of the past and near-term future of crewed space flight, as well as that of Earth and life. In the JAXA "Seeds in Space" experiments, the mutation effects of spaceflight on plant seeds aboard the ISS are explored by growing sunflower seeds that have flown on the ISS for about nine months. In the first phase of Kibō utilisation from 2008 to mid-2010, researchers from more than a dozen Japanese universities conducted experiments in diverse fields.

Cultural activities are another major objective of the ISS programme. Tetsuo Tanaka, the director of JAXA's Space Environment and Utilization Center, has said: "There is something about space that touches even people who are not interested in science."

Amateur Radio on the ISS (ARISS) is a volunteer programme that encourages students worldwide to pursue careers in science, technology, engineering, and mathematics, through amateur radio communications opportunities with the ISS crew. ARISS is an international working group, consisting of delegations from nine countries including several in Europe, as well as Japan, Russia, Canada, and the United States. In areas where radio equipment cannot be used, speakerphones connect students to ground stations which then connect the calls to the space station.

First Orbit is a feature-length documentary film about Vostok 1, the first crewed space flight around the Earth. By matching the orbit of the ISS to that of Vostok 1 as closely as possible, in terms of ground path and time of day, documentary filmmaker Christopher Riley and ESA astronaut Paolo Nespoli were able to film the view that Yuri Gagarin saw on his pioneering orbital space flight. This new footage was cut together with the original Vostok 1 mission audio recordings sourced from the Russian State Archive. Nespoli is credited as the director of photography for this documentary film, as he recorded the majority of the footage himself during Expedition 26/27. The film was streamed in a global YouTube premiere in 2011 under a free licence through the website firstorbit.org.

In May 2013, commander Chris Hadfield shot a music video of David Bowie's "Space Oddity" on board the station, which was released on YouTube. It was the first music video ever to be filmed in space.

In November 2017, while participating in Expedition 52/53 on the ISS, Paolo Nespoli made two recordings of his spoken voice (one in English and the other in his native Italian), for use on Wikipedia articles. These were the first content made in space specifically for Wikipedia.